Name :
GREM1 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to GREM1
Tested applications :
WB
Species reactivity :
Human
Alternative names :
GREM1 antibody; C15DUPq antibody; CKTSF1B1 antibody; CRAC1 antibody; CRCS4 antibody; DAND2 antibody; DRM antibody; DUP15q antibody; GREMLIN antibody; HMPS antibody; HMPS1 antibody; IHG-2 antibody; MPSH antibody; PIG2 antibody; gremlin-1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 44-143 of human GREM1 (NP_001178252.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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