Name :
Anti-Bax (2B12) Mouse antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Bax (2B12) Mouse monoclonal antibody
Tested applications :
WB
Species reactivity :
Human, Monkey
Alternative names :
Apoptosis regulator BAX; Apoptosis regulator BAX cytoplasmic isoform beta; Apoptosis regulator BAX membrane isoform alpha; BAX; Bax isoform psi; BAX protein cytoplasmic isoform delta; Bax protein cytoplasmic isoform delta.; Bax protein cytoplasmic isoform antibody
Immunogen :
Isotype :
IgG2a
Preparation :
Antigen: Purified recombinant human Bax protein fragments expressed in E.coli
Clonality :
Monoclonal
Formulation :
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000
Background :
Swiss-Prot Acc.Q07812.Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
References :
Aqueous extract of Fritillariae cirrhosae induces cellular apoptosis through activation of STATs-mediated immunomodulationSpleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome-mediated IL-1β secretion via c-Jun N-terminal kinase activation and cell apoptosis during diabetic nephropathy
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
M-CSF Antibody
Chk1 Antibody (YA505)
3-Nitrotyrosine Antibody: 3-Nitrotyrosine Antibody is an unconjugated, rabbit-derived, anti-3-Nitrotyrosine polyclonal antibody. 3-Nitrotyrosine Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, rat, and predicted: mouse background without labeling.
