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Name :
GTF2A2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GTF2A2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, HeLa cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 12kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
GTF2A2 antibody; HsT18745 antibody; TF2A2 antibody; TFIIA antibody; TFIIA 12 antibody; TFIIA gamma antibody; TFIIA p12 subunit antibody; TFIIAS antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GTF2A2 recombinant protein (Accession Number: NM_001320929). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200

Background :
Transcription mediated by RNA polymerase II depends on a set of different transcription factors to form the pre-initiation complex. TFIIA is involved in the construction of this complex and increases the affinity of TBP for the DNA union region [PMID:20480367]. TFIIA in a complex with TBP mediates transcriptional activity [PMID: 11030333]. GTF2A2 is one subunit of TFIIA.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel