Name :
GUSB antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GUSB Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, HL-60 cells, mouse heart tissue. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 78kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Beta G1 antibody; Beta glucuronidase antibody; FLJ39445 antibody; glucuronidase antibody; beta antibody; GUSB antibody; MPS7 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GUSB recombinant protein (Accession Number: NM_000181). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans.It is a tetrameric glycoprotein composed of identical subunits.GUSB plays an important role in the degradation of dermatan and keratan sulfates.It has two isoforms.
References :
Wang AL, Lukas TJ, Yuan M, Du N, Handa JT, Neufeld AH. Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration. PloS one. 4(4):e5304. 2009. Ishisaka A, Kawabata K, Miki S. Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages. PloS one. 8(11):e80843. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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