Name :
HACE1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HACE1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 78 kDa
Tested applications :
ELISA, WB, IF
Species reactivity :
Human; other species not tested.
Alternative names :
HACE1 antibody; KIAA1320 antibody
Immunogen :
Human HACE1 Recombinant protein (His tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HACE1 recombinant protein (Accession Number: NM_020771). Purification method: Antigen Affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IF: 1:20-1:200
Background :
HACE1(E3 ubiquitin-protein ligase HACE1) also named as KIAA1320, has a tumor-suppressor function dependent on its E3 ligase activity and controling adhesion-dependent growth and cell cycle progression during cell stress through degradation of cyclin D1. It belongs to the HECT family of E3 ubiqutin protein ligase. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 102 kDa, 36 kDa, 64 kDa and 78 kDa.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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