Name :
HAS3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HAS3 Rabbit Polyclonal antibody. Positive WB detected in L02 cells, mouse liver tissue. Observed molecular weight by Western-blot: 63kd
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
HA synthase 3 antibody; HAS3 antibody; hyaluronan synthase 3 antibody; Hyaluronate synthase 3 antibody; Hyaluronic acid synthase 3 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HAS3 recombinant protein (Accession Number: NM_138612). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
HAS3(hyaluronan synthase 3) belongs to the NodC/HAS family, which are widely expressed in human tissues and appear to function in embryogenesis, wound healing and other processes associated with cellular proliferation and migration(PMID:14566823). HAS3 is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. It may play a role in the progression of colon cancer and, as such, may provide novel targets for diagnostic and therapeutic interventions(PMID:14566823). It has 2 isoforms produced by alternative splicing and the protein has a glycosylation site.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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