Name :
HIP14; ZDHHC17 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HIP14; ZDHHC17 Rabbit Polyclonal antibody. Positive IHC detected in human testis. Positive WB detected in Raji cells, human kidney tissue. Observed molecular weight by Western-blot: 70kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
human, mouse, rat; other species not tested.
Alternative names :
ZDHHC17 antibody; HIP14 antibody; Palmitoyltransferase ZDHHC17 antibody; HIP 14 antibody; DHHC 17 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HIP14; ZDHHC17 recombinant protein (Accession Number: NM_015336). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Polyglutamine expansions of huntingtin protein are responsible for the Huntington neurological disorder. ZDHHC17 gene encodes palmitoyl transferase huntingtin interacting protein (HIP14) which regulates palmitoylation and distribution of hungtingtin. The latter is implicated in the formation of inclusion bodies and enhanced neuronal toxicity. HIP14 was also shown to control neurotransmitter release.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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