Name :
HLA class I (HLA-B) antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HLA class I (HLA-B) Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human spleen tissue, human heart tissue, human kidney tissue, human lung tissue, human ovary tissue. Positive IP detected in HepG2 cells. Positive WB detected in Jurkat cells, HeLa cells, HepG2 cells, MCF7 cells. Observed molecular weight by Western-blot: 40-45kd
Tested applications :
ELISA, WB, IHC, IF, IP
Species reactivity :
Human; other species not tested.
Alternative names :
HLA B antibody; HLA B 7301 antibody; HLA B73 antibody; HLAB antibody; HLA-B antibody; HLAC antibody; MHC class I antigen B*7 antibody; SPDA1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HLA class I (HLA-B) recombinant protein (Accession Number: BC013187). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:1000-1:10000IHC: 1:20-1:200IF: 1:20-1:200
Background :
Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa). They are involved in the presentation of foreign antigens to the immune system. (PMID: 667938; 3375250)
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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