Name :
HNRNPL antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HNRNPL Rabbit Polyclonal antibody. Positive WB detected in RAW 264.7 cells, mouse liver tissue. Positive IHC detected in human kidney tissue, human colon cancer tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 70 kDa
Tested applications :
ELISA, WB, IF, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
FLJ35509 antibody; hnRNP L antibody; HNRNPL antibody; HNRPL antibody; P/OKcl.14 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HNRNPL recombinant protein (Accession Number: BC069184). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100
Background :
Heterogeneous nuclear ribonucleoprotein L (hnRNP L) is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. It is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes. The two isoforms of hnRNP L are generated by alternative splicing.The human hnRNPL gene encodes a protein that is localized in the nucleoplasm and cytoplasm. This antibody may recognize both isoforms of the hnRNP L protein.
References :
Wang Y, Yue D, Xiao M. C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis. Journal of proteome research. 14(2):804-13. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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