Name :
HSD17B4 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HSD17B4 Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive IHC detected in human prostate cancer tissue, mouse heart tissue, mouse liver tissue. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue, mouse heart tissue, mouse liver tissue. Observed molecular weight by Western-blot: 79 kDa
Tested applications :
ELISA, WB, IHC, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
17 beta HSD 4 antibody; D bifunctional protein antibody; DBP antibody; EDH17B4 antibody; HSD17B4 antibody; MFE 2 antibody; SDR8C1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HSD17B4 recombinant protein (Accession Number: NM_000414). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100
Background :
HSD17B4 (17-beta-hydroxysteroid dehydrogenase 4) is also named as Peroxisomal multifunctional enzyme type 2, D-bifuntional protein or multifunctional protein 2. It codes for a 80 kDa enzyme containing three distinct functional domains and is localized in peroxisomes. It is a bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids and catalyzing the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-brancked-chian fatty acids.
References :
Verheijden S, Bottelbergs A, Krysko O. Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation. Neurobiology of disease. 58:258-69. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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