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Name :
Anti-Bim Rabbit antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Bim Rabbit polyclonal antibody

Tested applications :
WB, IHC-P, ICC/IF, IP, FC

Species reactivity :
Human, Mouse, Rat

Alternative names :

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthesized peptide derived from human Bim

Clonality :
Polyclonal

Formulation :
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Applications :
WB: 1/500-1/1000IHC: 1/50-1/100ICC/IF: 1/50-1/100IP: 1/40FC: 1/50

Background :
Swiss-Prot Acc.O43521.Bim a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel