Name :
HSP90 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HSP90 Mouse Monoclonal antibody. Positive WB detected in Y79 cells. Positive FC detected in K-562 cells. Observed molecular weight by Western-blot: 85-90 kDa
Tested applications :
ELISA, WB, FC
Species reactivity :
Human; other species not tested.
Alternative names :
FLJ31884 antibody; Heat shOCk 86 kDa antibody; HSP 86 antibody; HSP86 antibody; Hsp89 antibody; HSP89A antibody; HSP90 antibody; HSP90A antibody; HSP90AA1 antibody; HSP90N antibody; HSPC1 antibody; HSPCA antibody; HSPCAL1 antibody; HSPCAL4 antibody; HSPN antibody; LAP2 antibody
Immunogen :
Human HSP90 Recombinant protein (GST tag)
Isotype :
Mouse IgG2a
Preparation :
This antibody was obtained by immunization of HSP90 recombinant protein (Accession Number: BC023006). Purification method: Protein A purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000
Background :
HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.
References :
Ulanova A, Gritsyna Y, Vikhlyantsev I. Isoform composition and gene expression of thick and thin filament proteins in striated muscles of mice after 30-day space flight. BioMed research international. 2015:104735. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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