Share this post on:

Name :
HSPA4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HSPA4 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue, human breast cancer tissue, human pancreas cancer tissue. Positive IF detected in HepG2 cells. Positive IP detected in mouse brain tissue. Positive WB detected in L02 cells, A375 cells, HEK-293 cells, K-562 cells, mouse brain tissue, mouse kidney tissue, mouse liver tissue, mouse lung tissue, mouse ovary tissue, mouse testis tissue, NIH/3T3 cells, rat brain tissue. Observed molecular weight by Western-blot: 110-120kd

Tested applications :
ELISA, WB, IHC, IF, IP

Species reactivity :
Human,Mouse,Rat, Monkey; other species not tested.

Alternative names :
APG 2 antibody; APG2 antibody; Heat shOCk 70 kDa protein 4 antibody; heat shOCk 70kDa protein 4 antibody; HS24/P52 antibody; HSP70.4 antibody; hsp70RY antibody; HSPA4 antibody

Immunogen :
Human HSPA4 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HSPA4 recombinant protein (Accession Number: NM_002154). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
HSPA4 (also known as Apg-2, HSP70RY) is a 110 kDa cytosolic protein, a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA4 is ubiquitously expressed and its expression is not heat inducible. Overexpression of HSPA4 has been reported in some leukemia and solid tumors. This antibody well recognized the endogenous HSPA4 protein in mouse brain/ testis tissues. ( 21487003)

References :
Ullmann Y, Klein Y, Savulescu D. Salivary monitoring related to major surgery. European journal of clinical investigation. 40(12):1074-80. 2010.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
c-Fos Antibody (YA506)
Anti-Mouse Ly-6G/Ly-6C Antibody (RB6-8C5)
GLUT2 Antibody: GLUT2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 57 kDa, targeting to GLUT2. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human.

Share this post on:

Author: Gardos- Channel