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Name :
HuC antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HuC Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, mouse brain tissue. Positive IHC detected in human lung cancer tissue, human brain tissue. Observed molecular weight by Western-blot: 36-38kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
DKFZp547J036 antibody; ELAV like protein 3 antibody; ELAVL3 antibody; Hu antigen C antibody; HUC antibody; HUCL antibody; PLE21 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_001420). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
HUC , belongs to the RRM elav family. It binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. ELAVL3 may also bind poly-A tracts via RRM 3. It is involved in neuronal differentiation and maintenance. The antibody has no cross reaction to other ELAVL members.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel