Name :
ICOS antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
ICOS Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HL-60 cells. Observed molecular weight by Western-blot: 28 kDa, 45-50 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human; other species not tested.
Alternative names :
AILIM antibody; CD278 antibody; ICOS antibody; inducible T cell co stimulator antibody; Inducible T cell costimulator antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of ICOS recombinant protein (Accession Number: NM_012092). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000
Background :
Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation and for lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13. Catalog#13338-1-AP recognises two band of 25-30 kDa and 45-50 kDa, and the additional 45-50 kDa band may be due to glycosylation.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
RPA32 Antibody (YA679)
Bevacizumab
CD31 Antibody: CD31 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to CD31. It can be used for WB,IHC-P,FC,IP assays with tag free, in the background of Human.
