Name :
IDH2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IDH2 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human heart tissue. Positive WB detected in HEK-293 cells, DU 145 cells, Jurkat cells, mouse brain tissue, mouse liver tissue. Observed molecular weight by Western-blot: 47 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
ICD M antibody; IDH antibody; IDH2 antibody; IDHM antibody; IDP antibody; IDPM antibody; mNADP IDH antibody; NADP(+) specific ICDH antibody; Oxalosuccinate decarboxylase antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IDH2 recombinant protein (Accession Number: NM_002168). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200
Background :
IDH2, also named as IDP and ICD-M, belongs to the isocitrate and isopropylmalate dehydrogenases family. It plays a role in intermediary metabolism and energy production. IDH2 is a mitochondrial NADP-dependent isocitrate dehydrogenase that catalyzes oxidative decarboxylation of isocitrate to alpha-ketoglutarate, producing NADPH. It may tightly associate or interact with the pyruvate dehydrogenase complex. IDH1 and IDH2 mutations could also contribute to tumorigenesis and cancer progression through increased mutagenesis.This antibody is specific to IDH2.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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