Name :
IFIH1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IFIH1 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 117-125kd
Tested applications :
ELISA, WB, IP
Species reactivity :
Human; other species not tested.
Alternative names :
Helicard antibody; Helicase with 2 CARD domains antibody; Hlcd antibody; IDDM19 antibody; IFIH1 antibody; MDA 5 antibody; MDA5 antibody; RH116 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IFIH1 recombinant protein (Accession Number: NM_022168). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000
Background :
IFIH1 (Interferon-induced helicase C domain-containing protein 1) is a putative RNA helicase that is upregulated in response to treatment with IFNB or IFNB and MEZ. It is also named as MDA5 and RH116. Ectopic expression of MDA5 in melanoma cells resulted in reduced colony formation, suggesting an interaction of the CARD and apoptotic signal molecules. Functional analysis indicated that MDA5 is an RNA-dependent ATPase.This antibody is specific to IFIH1.
References :
Zhang W, Zhang L, Zan Y, Du N, Yang Y, Tien P. Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins. The Journal of general virology. 96(Pt 1):170-82. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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