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Name :
IFT27 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IFT27 Rabbit Polyclonal antibody. Positive WB detected in human RPE cells. Positive IHC detected in human brain tissue, human testis tissue. Positive IF detected in hTERT-RPE1 cells. Observed molecular weight by Western-blot: 20 kDa

Tested applications :
ELISA, WB, IF, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
IFT27 antibody; Rab like protein 4 antibody; RABL4 antibody; RAYL antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IFT27 recombinant protein (Accession Number: NM_001177701). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
RABL4, alo named as IFT27, is a GTP-binding protein that is a core component of the intraflagellar transport complex B. It plays a role in the cargo loading of the retrograde transport machinery.

References :
Raman M, Sergeev M, Garnaas M. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature cell biology. 17(10):1356-69. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel