Name :
IFT43 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IFT43 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
C14orf179 antibody; FLJ32173 antibody; IFT43 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IFT43 recombinant protein (Accession Number: NM_052873). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:20-1:200
Background :
IFT43, encoded by C14ORF179, is a subunit of the intraflagellar transport complex A (IFT-A) of primary cilia. The IFT-A is implicated in retrograde ciliary transport along axonemal microtubules. Defects in subunits of IFT-A has been associated with skeletal ciliopathies, including Sensenbrenner syndrome, Jeune syndrome, and Ellis-van-Creveld syndrome. Mutations in C14ORF179 has been linked to Sensenbrenner syndrome. (21378380)
References :
Luo N, Conwell MD, Chen X. Primary cilia signaling mediates intraocular pressure sensation. Proceedings of the National Academy of Sciences of the United States of America. 111(35):12871-6. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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