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Name :
IGFBP2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IGFBP2 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, PC-3 cells. Positive IF detected in HeLa cells. Positive IHC detected in human breast cancer tissue, human gliomas tissue, human prostate cancer tissue. Observed molecular weight by Western-blot: 32kd

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human; other species not tested.

Alternative names :

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IGFBP2 recombinant protein (Accession Number: NM_000597). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have important metabolic roles in the human body. IGFBP-2 is a 34 kD IGFBP protein with degarded fragments of 24 kD, 19kd and 15kd. The levels of IGFBP2 are elevated during progression of many human cancers. IGFBP2 is expressed in invasive PAc, whereas its expression in HG-PIN is low. It can be as an Immunohistochemical Marker for Prostatic Adenocarcinoma.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel