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Name :
IKBKB antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IKBKB Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Observed molecular weight by Western-blot: 87kd

Tested applications :
ELISA, WB

Species reactivity :
human, mouse, rat; other species not tested.

Alternative names :
IKBKB antibody; NFKBIKB antibody; IKK beta antibody; IKKB antibody; IKK B antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IKBKB recombinant protein (Accession Number: BC006231). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
IKBKB represents inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

References :
Zheng Z, Li H, Zhang Z. Enterovirus 71 2C protein inhibits TNF-α-mediated activation of NF-κB by suppressing IκB kinase β phosphorylation. Journal of immunology (Baltimore, Md. : 1950). 187(5):2202-12. 2011. Li Z, Wang Y, Newton IP, Zhang L, Ji P, Li Z. GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ. Cellular signalling. 27(6):1237-45. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel