Name :
IL-17 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IL-17 Mouse Monoclonal antibody. Positive FC detected in Jurkat cells. Positive WB detected in U-937 cells, Jurkat cells, Raji cells. Observed molecular weight by Western-blot: 18 kDa
Tested applications :
ELISA, WB, FC
Species reactivity :
Human, Rat; other species not tested.
Alternative names :
CTLA 8 antibody; CTLA8 antibody; IL 17 antibody; IL 17A antibody; IL17 antibody; IL-17 antibody; IL17A antibody; interleukin 17A antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of IL-17 recombinant protein (Accession Number: NM_002190). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Isatuximab
STING Antibody (YA048)
CD133 Antibody (YA809): CD133 Antibody (YA809) is a non-conjugated and Mouse origined monoclonal antibody about 97 kDa, targeting to CD133 (8F2). It can be used for WB assays with tag free, in the background of Human.
