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Name :
IL1R2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL1R2 Mouse Monoclonal antibody. Positive WB detected in HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 45KD

Tested applications :
ELISA, WB, IF

Species reactivity :
Human,Mouse; other species not tested.

Alternative names :
CD121b antibody; CDw121b antibody; IL 1R 2 antibody; IL 1R beta antibody; IL 1RT 2 antibody; IL 1RT2 antibody; IL1 Receptor 2 antibody; IL-1 Receptor 2 antibody; IL1 Receptor II antibody; IL-1 Receptor II antibody; IL1R2 antibody; IL1RB antibody; IL-1RII antibody; Interleukin 1 receptor beta antibody; Interleukin 1 receptor type 2 antibody; Interleukin 1 receptor type II antibody

Immunogen :

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of IL1R2 recombinant protein (Accession Number: NM_173343). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:20-1:200

Background :
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel