Share this post on:

Name :
IL21R antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL21R Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in K-562 cells, Jurkat cells. Observed molecular weight by Western-blot: 65 kDa

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human; other species not tested.

Alternative names :
CD360 antibody; IL 21 receptor antibody; IL 21R antibody; IL21R antibody; interleukin 21 receptor antibody; NILR antibody; Novel interleukin receptor antibody

Immunogen :

Isotype :
Mouse IgG2b

Preparation :
This antibody was obtained by immunization of IL21R recombinant protein (Accession Number: NM_181078). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:50-1:200

Background :
IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Calreticulin Antibody
CD68 Antibody (YA798)
V5-tag Antibody: V5-tag Antibody is a non-conjugated and Mouse origined monoclonal antibody, targeting to V5-tag. It can be used for WB,ELISA assays with V5-tag, in the background of .

Share this post on:

Author: Gardos- Channel