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Name :
IL22RA2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL22RA2 Mouse Monoclonal antibody. Positive IHC detected in human small intestine tissue, human breast cancer tissue, human lung cancer tissue. Positive WB detected in Raji cells. Observed molecular weight by Western-blot: 35 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
CRF2 10 antibody; CRF2 S1 antibody; CRF2X antibody; IL 22 receptor subunit alpha 2 antibody; IL 22BP antibody; IL 22R alpha 2 antibody; IL 22RA2 antibody; IL22BP antibody; IL22RA2 antibody; Interleukin 22 binding protein antibody; ZcytoR16 antibody

Immunogen :

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of IL22RA2 recombinant protein (Accession Number: NM_181309). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
Interleukin-22 receptor subunit alpha-2 (IL22RA2) is a soluble member of the type II cytokine receptor family. Through binding to IL22, IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel