Name :
IL23A antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IL23A Mouse Monoclonal antibody. Positive IHC detected in human pancreas tissue. Positive WB detected in Transfected HEK-293 cells. Observed molecular weight by Western-blot: 21 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
IL 23 antibody; IL 23 A antibody; IL 23 subunit alpha antibody; IL 23A antibody; IL 23p19 antibody; IL23A antibody; IL23P19 antibody; Interleukin 23 subunit alpha antibody; Interleukin 23 subunit p19 antibody; P19 antibody; SGRF antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of IL23A recombinant protein (Accession Number: NM_016584). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
IL23A is a subunit of the heterodimeric cytokine interleukin 23 (IL23), which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naïve T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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