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Name :
IL2RG antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL2RG Rabbit Polyclonal antibody. Positive FC detected in Jurkat cells. Positive WB detected in Jurkat cells, K-562 cells. Observed molecular weight by Western-blot: 42kd

Tested applications :
ELISA, WB, FC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
CD132 antibody; IL 2 receptor subunit gamma antibody; IL 2R subunit gamma antibody; IL 2RG antibody; IL2RG antibody; IMD4 antibody; p64 antibody; SCIDX antibody; SCIDX1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IL2RG recombinant protein (Accession Number: NM_000206). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL2RA), beta (IL2RB), and gama (IL2RG). IL2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel