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Name :
Importin beta antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Importin beta Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive WB detected in mouse brain tissue, A2780 cells, HeLa cells, HT-1080 cells, rat brain tissue. Observed molecular weight by Western-blot: 90-97 kDa

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human, Mouse, Rat; other species not tested.

Alternative names :
IMB1 antibody; Impnb antibody; Importin 90 antibody; Importin subunit beta 1 antibody; IPO1 antibody; IPOB antibody; karyopherin (importin) beta 1 antibody; Karyopherin subunit beta 1 antibody; KPNB1 antibody; NTF97 antibody; Nuclear factor p97 antibody; PTAC97 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Importin beta recombinant protein (Accession Number: NM_002265). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
Importin beta1, also known karyopherin beta or KPNB1, is a nuclear transport receptor that plays a key role in the nuclear import process. Importin beta1 and importin alpha work in concert to transport cargo into the nucleus, functioning as an essential component of the classical nuclear localization signal (NLS) pathway. Elevated expression of importin beta1 has been found in cervical tumors. (22125623)

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel