Name :
ING1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
ING1 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, A375 cells. Observed molecular weight by Western-blot: 47 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
ING1 antibody; Inhibitor of growth protein 1 antibody; p24ING1c antibody; p33 antibody; p33ING1 antibody; p33ING1b antibody; p47 antibody; p47ING1a antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of ING1 recombinant protein (Accession Number: NM_198219). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
ING1, also inhibitor of growth protein 1, is a 422 amino acid protein, which contains 1 PHD-type zinc finger and belongs to the ING family. ING1 localizes in the nucleus and interacts with TP53. It exsits as varous isoforms and isoform 1 is a 47 kDa protein. Isoform 2 is a 33 kDa protein and expressed in all normal tissues, as well as in all breast cancer and melanoma cell lines examined. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. It is implicated as a tumor suppressor gene.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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