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Name :
ING3-specific antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
ING3-specific Rabbit Polyclonal antibody. Positive IP detected in mouse kidney tissue. Positive WB detected in human kidney tissue, mouse heart tissue, mouse kidney tissue, mouse liver tissue. Observed molecular weight by Western-blot: 46 kDa

Tested applications :
ELISA, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Eaf4 antibody; FLJ20089 antibody; ING2 antibody; ING3 antibody; Inhibitor of growth protein 3 antibody; p47ING3 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_019071). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000

Background :
Members of inhibitor of growth (ING) family function in inhibiting cell growth and inducing apoptosis. They are sequence homologous proteins. ING3 can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. This antibody is specifically against p47ING3.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel