Name :
INO80 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
INO80 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, mouse brain tissue. Observed molecular weight by Western-blot: 178kd
Tested applications :
ELISA, WB
Species reactivity :
human, mouse, rat; other species not tested.
Alternative names :
INO80 antibody; INO80A antibody; INO80 homolog (S. cerevisiae) antibody; KIAA1259 antibody; INOC1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_017553). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
INO80, also named as INoc1 and KIAA1259, belongs to the SNF2/RAD54 helicase family. The INO80 complex remodels chromatin by shifting nucleosomes. INO80 recruited by YY1 to YY1-activated INO80. In vitro, INO80 has double stranded DNA-dependent ATPase activity
References :
Wang L, Du Y, Ward JM. INO80 facilitates pluripotency gene activation in embryonic stem cell self-renewal, reprogramming, and blastocyst development. Cell stem cell. 14(5):575-91. 2014. Serber DW, Runge JS, Menon DU, Magnuson T. The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis. Biology of reproduction. 94(1):8. 2016.
Related websites: https://www.medchemexpress.com/antibodies.html
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