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Name :
Integrin beta-1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Integrin beta-1 Mouse Monoclonal antibody. Positive WB detected in HT-1080 cells, HUVEC cells. Observed molecular weight by Western-blot: 130 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
CD29 antibody; FNRB antibody; GPIIA antibody; Integrin beta 1 antibody; Integrin beta-1 antibody; ITGB1 antibody; MDF2 antibody; MSK12 antibody; VLA 4 subunit beta antibody; VLA BETA antibody; VLAB antibody

Immunogen :

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of Integrin beta-1 recombinant protein (Accession Number: NM_002211). Purification method: Protein G purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:2000-1:20000

Background :
Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel