Name :
IP6K2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IP6K2 Rabbit Polyclonal antibody. Positive WB detected in human adrenal gland tissue, human heart tissue, K-562 cells. Observed molecular weight by Western-blot: 49kd
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
IHPK2 antibody; InsP6 kinase 2 antibody; IP6K2 antibody; P(i) uptake stimulator antibody; PiUS antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IP6K2 recombinant protein (Accession Number: XM_017006585). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
IP6K2(Inositol hexakisphosphate kinase 2) is also named as IHPK2, PiUS and belongs to the inositol phosphokinase (IPK) family. It converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) and and mediates apoptotic cell death via its translocation from the nucleus to the cytoplasm(PMID:21652713). IP6K2 regulates TP53 and protein kinase AKT signaling, and its aberrant increase in cells has been implicated in apoptosis and insulin resistance(PMID:21262846). It has 6 isoforms produced by alternative splicing. This antibody recognizes the others except the 8 kDa isoform of IP6K2.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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