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Name :
iPLA2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
iPLA2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Positive IP detected in mouse testis tissue. Positive IHC detected in human small intestine tissue, human brain tissue. Observed molecular weight by Western-blot: 80 kDa,88 kDa

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
CaI PLA2 antibody; Group VI phospholipase A2 antibody; GVI antibody; GVI PLA2 antibody; INAD1 antibody; iPLA2 antibody; IPLA2 VIA antibody; PARK14 antibody; PLA2 antibody; PLA2G6 antibody; PNPLA9 antibody

Immunogen :
Human PLA2G6 Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of iPLA2 recombinant protein (Accession Number: XM_005261764). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
PLA2G6, also named as PLPLA9, is involved in the remodeling of membranes allowing arachidonic acid to be placed in the proper position in phospholipids for stimulated release. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. This protein has 4 isoforms produced by alternative splicing.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel