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Name :
IQGAP1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IQGAP1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, A549 cells, HEK-293 cells, HepG2 cells, Jurkat cells, NIH/3T3 cells, SGC-7901 cells. Positive IF detected in HeLa cells. Positive IHC detected in human kidney tissue, human liver cancer tissue. Observed molecular weight by Western-blot: 190-195 kDa

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
HUMORFA01 antibody; IQGAP1 antibody; KIAA0051 antibody; p195 antibody; SAR1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IQGAP1 recombinant protein (Accession Number: NM_003870). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200

Background :
IQGAP1 represents IQ motif containing GTPase activating protein 1

References :
Moon H, Ruelcke JE, Choi E. Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1. Oncotarget. 6(10):7438-53. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel