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Name :
IRF1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IRF1 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, Jurkat cells. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 45-50 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
interferon regulatory factor 1 antibody; IRF 1 antibody; IRF1 antibody; MAR antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IRF1 recombinant protein (Accession Number: NM_002198). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200

Background :
IRF1 represents interferon regulatory factor 1

References :
Yuan L, Zhou C, Lu Y. IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1. Cancer letters. 359(1):136-47. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel