Name :
IRF2 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to IRF2
Tested applications :
WB
Species reactivity :
Human, Mouse
Alternative names :
IRF2 antibody; IRF-2 antibody; interferon regulatory factor 2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human IRF2
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, pH7.3.
Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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