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Name :
IRF4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IRF4 Rabbit Polyclonal antibody. Positive FC detected in Raji cells. Positive IHC detected in human lymphoma tissue, human tonsillitis tissue. Positive WB detected in mouse spleen tissue, Jurkat cells, mouse lung tissue, mouse thymus tissue, Raji cells, RAW264.7 cells. Positive IP detected in mouse spleen tissue. Observed molecular weight by Western-blot: 50-52 kDa

Tested applications :
ELISA, IHC, WB, IP, FC

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
interferon regulatory factor 4 antibody; IRF 4 antibody; IRF4 antibody; LSIRF antibody; Multiple myeloma oncogene 1 antibody; MUM1 antibody; NF EM5 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IRF4 recombinant protein (Accession Number: NM_002460). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
Interferon regulatory factor 4 (IRF4) is a member of the IRF family of transcription factors, expressed in most cell types of the immune system. IRF4 is a transcription factor essential for the development of T helper-2 (Th2) cells, IL17-producing Th17 cells, and IL9-producing Th9 cells, as well as dendritic cell (DC). It binds to and activates the interferon-stimulated response element (ISRE) of the MHC class I promoter, and may have a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel