Name :
ITPKB antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
ITPKB Rabbit Polyclonal antibody. Positive IHC detected in human cervical cancer tissue. Positive WB detected in mouse brain tissue, K-562 cells, mouse lung tissue, mouse thymus tissue, rat brain tissue. Observed molecular weight by Western-blot: 102-110 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
InsP 3 kinase B antibody; IP3 3 kinase B antibody; IP3K antibody; IP3K B antibody; IP3KB antibody; ITPKB antibody; PIG37 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of ITPKB recombinant protein (Accession Number: NM_001388404). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
Inositol 1,4,5-trisphosphate 3-kinase isoform B (IITPKB) is also named as IP3KB and possesses important roles in the development of immune cells. IP3KB can be targeted to multiple cellular compartments, among them nuclear localization and binding in close proximity to the plasma membrane. The B isoform is the only IP3K that is almost ubiquitously expressed in mammalian cells(PMID:21148483).Three isoforms of IP3KB occur in mammals, which are distinguished by different molecular masses, sensitivity to Ca2+/CaM(calmodulin), intracellular distribution and tissue expression (PMID:16173920).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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