Name :
JUNB antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
JUNB Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in MCF7 cells, C6 cells, HeLa cells, HT-1080 cells. Positive IHC detected in human gliomas tissue, human ovary tissue, human testis tissue. Positive IF detected in MCF-7 cells, HeLa cells. Observed molecular weight by Western-blot: 42 kDa, 43 kDa
Tested applications :
ELISA, WB, IHC, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
AP 1 antibody; jun B proto oncogene antibody; JUNB antibody; Transcription factor jun B antibody
Immunogen :
Human JUNB Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of JUNB recombinant protein (Accession Number: NM_002229). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100
Background :
JunB is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. AP-1 is a collection of dimers formed by members of the Jun-, Fos-, ATF- and Maf multigene families that bind to specific DNA regulatory elements called AP-1/12-O-tetradecanoylphorbol-13-acetate-responsive elements (TREs) and cAMP-responsive elements (CREs). JunB binds to the DNA sequence 5′-TGA[CG]TCA-3′, and involves in the regulation of gene activity following the primary growth factor response. It also acts either as a tumor suppressor or as an oncogene depending on the cell and physiopathological context
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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