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Name :
Kallikrein 8 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Kallikrein 8 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 30 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
hK8 antibody; HNP antibody; Kallikrein 8 antibody; kallikrein related peptidase 8 antibody; KLK8 antibody; Neuropsin antibody; NRPN antibody; Ovasin antibody; PRSS19 antibody; Serine protease 19 antibody; Serine protease TADG 14 antibody; TADG14 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Kallikrein 8 recombinant protein (Accession Number: NM_007196). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:50-1:500

Background :
KLK8(Kallikrein-8) is also named as NRPN, PRSS19, TADG14.It is a new member of the human kallikrein family,which is predicted to be secreted and expected to be present in biological fluids(PMID:12507964).The protein is detectable in ovarian cancer tissue extracts, serum, and ascites fluid, indicating that it may serve as a new ovarian cancer marker(PMID:12782581).KLK8 has one predicted glycosylation site(PMID:20940292) and it has 4 isoforms produced by alternative splicing.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel