Name :
KALRN antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KALRN Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, human kidney tissue, mouse colon tissue. Observed molecular weight by Western-blot: 200kd
Tested applications :
ELISA, WB
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
DUET antibody; duo antibody; FLJ16443 antibody; HAPIP antibody; Kalirin antibody; kalirin antibody; RhoGEF kinase antibody; KALRN antibody; Protein Duo antibody; TRAD antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_007064). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
KALRN, also named as DUET, DUO, HAPIP and TRAD, belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. KALRN promotes the exchange of GDP by GTP. KALRN activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. KALRN induces lamellipodia independent of its GEF activity. The antibody can recognize isoform1 and isoform2 of KALRN.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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