Name :
KANK2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KANK2 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive WB detected in mouse lung tissue, mouse heart tissue, mouse kidney tissue, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 95kd
Tested applications :
ELISA, WB, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
ANKRD25 antibody; DKFZp434N161 antibody; FLJ20004 antibody; KANK2 antibody; KIAA1518 antibody; MXRA3 antibody; SIP antibody; SRC 1 interacting protein antibody; SRC1 interacting protein antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KANK2 recombinant protein (Accession Number: NM_001379563). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:10-1:100
Background :
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.
References :
Yasuda K, Zhang H, Loiselle D, Haystead T, Macara IG, Mili S. The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules. The Journal of cell biology. 203(5):737-46. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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