Name :
KCNJ2 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to KCNJ2
Tested applications :
WB, IHC
Species reactivity :
Human, Mouse, Rat
Alternative names :
KCNJ2 antibody; ATFB9 antibody; HHBIRK1 antibody; HHIRK1 antibody; IRK1 antibody; KIR2.1 antibody; LQT7 antibody; SQT3 antibody; inward rectifier potassium channel 2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 318-427 of human KCNJ2 (NP_000882.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200
Background :
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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