Name :
KCNK18 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KCNK18 Rabbit Polyclonal antibody. Positive WB detected in A431 cells, A375 cells, MCF-7 cells. Observed molecular weight by Western-blot: 44 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human; other species not tested.
Alternative names :
K2p18.1 antibody; KCNK18 antibody; TRESK antibody; TRESK 2 antibody; TRESK2 antibody; TRIK antibody
Immunogen :
Human KCNK18 Recombinant protein (His tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KCNK18 recombinant protein (Accession Number: NM_181840). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
KCNK18, also named as TRESK and TRIK, is an outward rectifying potassium channel which produces rapidly activating outward rectifier K+ currents. It may function as background potassium channel that sets the resting membrane potential. KCNK18 is inhibited by arachidonic acid and other naturally occurring unsaturated free fatty acids. KCNK18 channel activity is enhanced by volatile anesthetics, such as isoflurane. The gene of KCNK18 maps to chromosome 10q26.11, and encodes a 384-amino acid protein with a predicted unmodified molecular weight of 44 kDa. This antibody can be used to detect endogenous KCNK18, however, the reason for the additional band of 130-140 kDa is still unknown.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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