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Name :
KIFAP3 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KIFAP3 Mouse Monoclonal antibody. Positive WB detected in human testis tissue. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 91-100kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse, Rat; other species not tested.

Alternative names :
dJ190I16.1 antibody; FLJ22818 antibody; KAP 3 antibody; KAP3 antibody; KIF3AP antibody; KIFAP3 antibody; kinesin assOCiated protein 3 antibody; SMAP antibody; Smg GDS antibody; Smg GDS assOCiated protein antibody

Immunogen :

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of KIFAP3 recombinant protein (Accession Number: NM_014970). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
KIFAP3, also known as KIF3AP or KAP3, is a novel KIF3A/3B-associated protein. It binds to the tail domain of KIF3A/3B and may play a role in regulating the binding of KIF3A/3B to cargoes. Recently it has been reported that mutation within the KIFAP3 gene is associated with decreased KIFAP3 expression and increased survival in sporadic ALS, which makes it a potential target for ALS therapy. KIFAP3 has also been identified as the target of mir-130a.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel