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Name :
KIR2DS4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KIR2DS4 Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells, Jurkat cells. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 33 kDa

Tested applications :
ELISA, WB, IF

Species reactivity :
Human; other species not tested.

Alternative names :
CD158I antibody; KIR1D antibody; KIR2DS4 antibody; KIR412 antibody; KKA3 antibody; MHC class I NK cell receptor antibody; NKAT 8 antibody; NKAT8 antibody; p58 NK receptor CL 39/CL 17 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KIR2DS4 recombinant protein (Accession Number: NM_012314). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IF: 1:10-1:100

Background :
KIR2DS4 (also known as CD158i) is a member of the killer cell immunoglobulin-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIRs are mainly involved in inhibiting NK killing (inhibitory KIRs) via interaction with MHC class I molecules. KIR2DS4 has been reported to be an activating KIR and recognize the HLA-Cw4 protein.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel