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Name :
KIR3DL1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KIR3DL1 Rabbit Polyclonal antibody. Positive FC detected in Jurkat cells. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 49 kDa

Tested applications :
ELISA, WB, FC

Species reactivity :
Human; other species not tested.

Alternative names :
CD158E antibody; CD158E1 antibody; KIR antibody; KIR3DL1 antibody; MHC class I NK cell receptor antibody; NKAT 3 antibody; NKAT3 antibody; NKB1 antibody; NKB1B antibody; p70 NK receptor CL 2/CL 11 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KIR3DL1 recombinant protein (Accession Number: NM_013289). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against 22-344 amino acids of human KIR3DL1 and recognizes both KIR3DL1 (49 kDa) and KIR3DS1 (43 kDa).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel