Name :
KISS1R-Specific antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KISS1R-Specific Rabbit Polyclonal antibody. Positive IF detected in MCF-7. Positive WB detected in SH-SY5Y cells, MCF7 cells. Observed molecular weight by Western-blot: 43-45kd,75kd
Tested applications :
ELISA, WB, IF
Species reactivity :
human; other species not tested.
Alternative names :
KISS1R antibody; KISS1 receptor antibody; HOT7T175 antibody; Hypogonadotropin 1 antibody; AXOR12 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_032551). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:10-1:100
Background :
receptor for metastin (kisspeptin-54, 13, 14, 10), C- terminally amidated peptides of KiSS-1. KiSS-1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some other carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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