Name :
KLF5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KLF5 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IP detected in HeLa cells. Positive WB detected in HeLa cells, A549 cells, HT-1080 cells, human testis tissue, mouse colon tissue, mouse small intestine tissue, PC-3 cells. Observed molecular weight by Western-blot: 50-60 kDa
Tested applications :
ELISA, IP, IF, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
BTE binding protein 2 antibody; BTEB2 antibody; CKLF antibody; Colon krueppel like factor antibody; GC box binding protein 2 antibody; IKLF antibody; KLF5 antibody; Krueppel like factor 5 antibody; Transcription factor BTEB2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KLF5 recombinant protein (Accession Number: NM_001730). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IF: 1:50-1:500
Background :
KLF5, also known as BTEB2 and IKLF, is a member of the Krueppel-like transcription factor family. It is a transcription factor for SMemb/non-muscle myosin heavy chain-B (NMHC-B). It is a molecular marker of phenotypically modulated smooth-muscle cells. KLF5 seems to be a key element linking external stress and cardiovascular remodeling. This antibody detects the 50-60 kDa isoform 1 of KLF5. The antibody can recognize isoform 2 (33 kDa) and isoform 3 (18 kDa) too.
References :
Ji S, Qin Y, Shi S. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer. Cell research. 25(5):561-73. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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